Speeding up the translation from bench to bedside
Objective:
Improve the translational approach in research to increase the number of new treatments and prevention strategies that will become available in health care for OA patients.
Task 2.1: Technical and economic hurdles associated with the establishment and implementation of translational research models (crossing the Valley of Death).
Task 2.2: Guidelines for data collection, sampling, phenotyping, endotyping and clinical trial designs for companies bringing products targeting OA to the market to avoid common repeated failures in phase 2 and 3 clinical trials.
Task 2.3: Identification of the major challenges associated with translation from preclinical models to humans without intermediate translational models.
Task 2.4: European Consensus on Chronic Disease Self-Management Program CDSMP program for OA prevention.